DIETHYL (2S,3S)-2,3-EPOXYSUCCINATE
diethyl (2S,3S)-oxirane-2,3-dicarboxylate
CAS: 73890-18-3
Molecular Formula: C8H12O5
DIETHYL (2S,3S)-2,3-EPOXYSUCCINATE - Names and Identifiers
DIETHYL (2S,3S)-2,3-EPOXYSUCCINATE - Physico-chemical Properties
| Molecular Formula | C8H12O5 |
| Molar Mass | 188.18 |
| Density | 1.233±0.06 g/cm3(Predicted) |
| Boling Point | 233.7±30.0 °C(Predicted) |
| Flash Point | 95.5°C |
| Vapor Presure | 0.0549mmHg at 25°C |
| Refractive Index | 1.437-1.439 |
DIETHYL (2S,3S)-2,3-EPOXYSUCCINATE - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| HS Code | 29189990 |
DIETHYL (2S,3S)-2,3-EPOXYSUCCINATE - Introduction
Diethyl (2S,3S)-( )-2,3-epoxysuccinic acid, chemical formula C10H16O5, is an organic compound. The following is a detailed description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Colorless or light yellow liquid
-Density: 1.161g/cm3
-Melting point:-6 ℃
-Boiling point: 165-166 ℃
-Solubility: Soluble in ethanol, ether, dichloromethane and benzene and other non-polar solvents
Use:
-Diethyl (2S,3S)-( )-2,3-epoxysuccinic acid is a chiral radioactive medium, which is commonly used in imaging techniques such as nuclear magnetic resonance.
-It can also be used as a chemical intermediate for organic synthesis reactions, especially for chiral synthesis and high-performance liquid chromatography separation.
Preparation Method:
Diethyl (2S,3S)-( )-2,3-epoxysuccinic acid can be prepared by the following steps:
1. First, 2,3-bis (ethyloxycarbonyl)-succinic anhydride is reacted with a chiral catalyst (such as an acidic or basic catalyst) to generate diethyl (2S,3S)-( )-2,3-epoxysuccinic acid.
Safety Information:
-Diethyl (2S,3S)-( )-2,3-epoxysuccinic acid has low toxicity, but should still follow laboratory safety procedures.
-Avoid contact with skin and eyes. If contact occurs, rinse immediately with plenty of water.
-storage should be sealed, away from fire and oxidant, and stored in a cool, dry place.
-It is recommended to use in a ventilated place and wear appropriate personal protective equipment, such as gloves and protective glasses.
Nature:
-Appearance: Colorless or light yellow liquid
-Density: 1.161g/cm3
-Melting point:-6 ℃
-Boiling point: 165-166 ℃
-Solubility: Soluble in ethanol, ether, dichloromethane and benzene and other non-polar solvents
Use:
-Diethyl (2S,3S)-( )-2,3-epoxysuccinic acid is a chiral radioactive medium, which is commonly used in imaging techniques such as nuclear magnetic resonance.
-It can also be used as a chemical intermediate for organic synthesis reactions, especially for chiral synthesis and high-performance liquid chromatography separation.
Preparation Method:
Diethyl (2S,3S)-( )-2,3-epoxysuccinic acid can be prepared by the following steps:
1. First, 2,3-bis (ethyloxycarbonyl)-succinic anhydride is reacted with a chiral catalyst (such as an acidic or basic catalyst) to generate diethyl (2S,3S)-( )-2,3-epoxysuccinic acid.
Safety Information:
-Diethyl (2S,3S)-( )-2,3-epoxysuccinic acid has low toxicity, but should still follow laboratory safety procedures.
-Avoid contact with skin and eyes. If contact occurs, rinse immediately with plenty of water.
-storage should be sealed, away from fire and oxidant, and stored in a cool, dry place.
-It is recommended to use in a ventilated place and wear appropriate personal protective equipment, such as gloves and protective glasses.
Last Update：2024-04-10 22:29:15
